This method is applicable to exchange users only. Locate the following programs and uninstall them.
#Permission denied openin windows
If it still won’t work then Hold the Windows Key and Press R. Uncheck all the items in Add-Ins available list and click OK. To disable add-ins, click File -> Options -> Add-ins -> COM Add-ins -> Manage -> Go. Disable all add-ins and then open Outlook to confirm, if it works then enable add-in one by one until you get to the one which stops Outlook. If it works in Safe Mode, then the is likely to be a conflicting or corrupt add-in. If there is only one profile, then it will be selected by default. You will be asked which profile to use when logging in. 
In the run dialog, type outlook.exe /safe and press Enter.
Now open Outlook to see if it works or not, if it still won’t work, then proceed with Method 2. Right-click the Outlook.xml file and choose rename, and add. In the run dialog box type %appdata%\Microsoft\Outlook To do this, Hold the Windows Key and Press R. If it still won’t open after resetting the navigation pane, or if it gives an error, close/exit out of any error pop-ups and rename the Outlook.xml file to. In the run dialog, type, and press Enter. In this solution, we will reset the navigation pane settings in Outlook. If you do, then try the other method listed below. Add-in’s can also interrupt Outlook from accessing the data file.ĭownload and run Restoro to scan and repair corrupt/missing files from here, if files are found to be corrupt and missing repair them and then see if you still get the error on Outlook. Secondly, make sure that the file has not been moved from it’s original location. 
Before going through the steps listed below, make sure that you are not running any back up software’s that is supposed to backup the data file, because if the file is in use, then Outlook will not be able to access the file. The operation failed.” usually indicates that the outlook data file, where outlook has all the information stored cannot be opened. Outlook users getting error “ Cannot start Microsoft Outlook.
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